Select one or more newsletters to continue. Explore Apps. About About Drugs. Follow Drugs. All rights reserved. Sildenafil citrate Viagra; Pfizer Inc, New York, NY relaxes vascular smooth muscle, Androgel, resulting in modest reductions in blood pressure Testosterone Gel dose are Testosterone Gel 1% to stimulate a reflex increase in heart rate. These blood pressure reductions are similar for healthy men and men with coronary artery disease CAD or who use antihypertensive drugs. Sildenafil does not affect the force of cardiac contraction, and cardiac performance is unaffected. Sildenafil is mildly vasodilating in the coronary circulation and does not increase the risk of ventricular arrhythmia. During exercise and recovery, sildenafil does not cause clinically significant alterations in hemodynamic parameters in men with CAD, and it has no negative effects on coronary oxygen consumption, ischemia, or exercise capacity.